Does Creatine Cause Constipation? Creatine is a popular supplement used by athletes and bodybuilders to increase muscle mass mass. While it has been confirmed to be successful in helping people Develop toughness, there are some potential Uncomfortable side effects that have been linked with creatine use, which includes constipation. https://wellnessprosper.com/does-creatine-cause-constipation-exploring-the-potential-link/